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Sequestosome 1 (SQSTM1) Antibody
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Catalogue No: abx031056
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Research Articles on Sequestosome 1 (SQSTM1)
| Target | Sequestosome 1 (SQSTM1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 383-409 amino acids from the C-terminal region of human SQSTM1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13501 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NFN7, B2R661, B3KUW5, Q13446, Q9BUV7, Q9BVS6, Q9UEU1 |
| UniProt Entry Name | SQSTM_HUMAN |
| KEGG | hsa:8878 |
| String | 9606.ENSP00000374455 |
| Molecular Weight | Calculated MW: 47.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat SQSTM1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |