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Steroid Receptor Rna Activator 1 (SRA) Antibody
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Catalogue No: abx016058
Price:
US$420.50
(Size: 100 µl)
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Steroid receptor RNA activator 1 (SRA), with 237-amino acid protein (about 27kDa), belongs to the growing family of functional non-coding RNAs.SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors.Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein.Its expression is strongly up-regulated in many human tumors of the breast, uterus, and ovary, suggesting a potential role in pathogenesis.Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis.
Research Articles on Steroid Receptor Rna Activator 1 (SRA)
| Target | Steroid Receptor Rna Activator 1 (SRA) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of SRA expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9HD15 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6NVU9, Q8IXM1, Q9HD13, Q9HD14 |
| UniProt Entry Name | SRA1_HUMAN |
| Gene Symbol | SRA1 |
| GeneID | 10011 |
| OMIM | 603819 |
| HGNC | 11281 |
| Ensembl | ENSG00000213523 |
| String | 9606.ENSP00000337513 |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |