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SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC) Antibody
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Catalogue No: abx025552
Price:
US$326.25
(Size: 80 µl)
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This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Research Articles on SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC)
| Target | SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein encoding full length human SRC. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P12931 (UniProt, ExPASy) |
| UniProt Secondary AC | E1P5V4, Q76P87, Q86VB9, Q9H5A8 |
| NCBI Accession | NP_005408.1 NP_938033.1 |
| Molecular Weight | Calculated MW: 59.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |