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SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC) Antibody
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Catalogue No: abx012188
Price:
US$406.00
(Size: 100 µg)
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SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC) Antibody is a Rabbit Polyclonal antibody for the detection of SRC. SRC, also named as SRC1 and p60-Src, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, SRC plays an important role in osteoclastic bone resorption. It promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase.
Research Articles on SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC)
| Target | SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | v-src sarcoma(Schmidt-Ruppin A-2) viral oncogene homolog |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P12931 (UniProt, ExPASy) |
| UniProt Secondary AC | E1P5V4, Q76P87, Q86VB9, Q9H5A8 |
| Gene Symbol | SRC |
| GeneID | 6714 |
| OMIM | 190090 |
| HGNC | 11283 |
| Ensembl | ENSG00000197122 |
| Molecular Weight | Observed MW: 55 kDa, 60 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |