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Serrate RNA Effector Molecule Homolog (SRRT) Antibody
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Catalogue No: abx029383
Price:
US$290.00
(Size: 80 µl)
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SRRT acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and RNASEN, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA) ; however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.
Research Articles on Serrate RNA Effector Molecule Homolog (SRRT)
| Target | Serrate RNA Effector Molecule Homolog (SRRT) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 54-81 amino acids from the N-terminal region of human SRRT. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9BXP5 (UniProt, ExPASy) |
| UniProt Entry Name | SRRT_HUMAN |
| Gene Symbol | SRRT |
| String | 9606.ENSP00000480421 |
| Molecular Weight | Calculated MW: 101 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Cow SRRT. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |