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Sex-Determining Region Y Protein (SRY) Antibody
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Catalogue No: abx012234
Price:
US$420.50
(Size: 100 µl)
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This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome);.
Research Articles on Sex-Determining Region Y Protein (SRY)
| Target | Sex-Determining Region Y Protein (SRY) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human SRY (AA:1-204) expressed in E. Coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q05066 (UniProt, ExPASy) |
| UniProt Entry Name | SRY_HUMAN |
| Gene Symbol | SRY |
| GeneID | 6736 |
| OMIM | 400044 |
| HGNC | 11311 |
| KEGG | hsa:6736 |
| Ensembl | ENSG00000184895 |
| Molecular Weight | 23.9 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |