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Structure Specific Recognition Protein 1 (SSRP1) Antibody
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Catalogue No: abx004907
Price:
US$348.00
(Size: 60 µl)
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SSRP1 Antibody is a Rabbit Polyclonal antibody against SSRP1. The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
Research Articles on Structure Specific Recognition Protein 1 (SSRP1)
| Target | Structure Specific Recognition Protein 1 (SSRP1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/10 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human SSRP1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q08945 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5BJG8 |
| UniProt Entry Name | SSRP1_HUMAN |
| Gene Symbol | SSRP1 |
| GeneID | 6749 |
| NCBI Accession | NP_003137.1 |
| KEGG | hsa:6749 |
| String | 9606.ENSP00000278412 |
| Molecular Weight | Calculated MW: 81 kDa Observed MW: 98 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
