Signal Transducer and Activator of Transcription 2 Phospho-Tyr690 (STAT2 pY690) Antibody

REQUEST MORE INFO
Catalogue No: abx000335
Price: US$797.50
(Size: 96 tests)

Orders to United States ship from United States

Reviews: 0 Publications and Reviews
(0 Publications and Reviews)
Western blot analysis of lysates from HeLa cells, using Phospho-STAT2-Y690 Antibody at 1/500 dilution.HeLa cells were treated by IFN-α (100 ng/ml) at 37 °C for 30 minutes after serum-starvation overnight. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Exposure time: 60s.
Signal Transducer and Activator of Transcription 2 Phospho-Tyr690 (STAT2 pY690) Antibody

Click on the image to see the image legend

Available Options

* Size:



Add to Shopping Cart Buy It Now GET A QUOTE

Documents

Datasheet SDS
STAT2 (pY690) Antibody is a Rabbit Polyclonal antibody against STAT2 (pY690). The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.

Target Signal Transducer and Activator of Transcription 2 Phospho-Tyr690 (STAT2 pY690)
Clonality Polyclonal
Target Modification Tyr690
Modification Phosphorylation
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic phosphorylated peptide around Y690 of human STAT2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P52630 (UniProt, ExPASy)
UniProt Secondary AC B4DLC7, G3V2M6, Q16430, Q16431, Q9UDL4
UniProt Entry Name STAT2_HUMAN
Gene Symbol STAT2
GeneID 6773
NCBI Accession NP_005410.1
KEGG hsa:6773
String 9606.ENSP00000315768
Molecular Weight Calculated MW: 98 kDa
Observed MW: 97 kDa
Buffer PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Signal Transducer and Activator of Transcription 2 Phospho-Tyr690 (STAT2 pY690)
Tags:
(Click to show)