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Signal Transducer And Activator of Transcription 4 (STAT4) Antibody
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Catalogue No: abx005299
Price:
US$203.00
(Size: 20 µl)
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STAT4 Antibody is a Rabbit Polyclonal antibody against STAT4. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
Research Articles on Signal Transducer And Activator of Transcription 4 (STAT4)
| Target | Signal Transducer And Activator of Transcription 4 (STAT4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 569-748 of human STAT4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14765 (UniProt, ExPASy) |
| UniProt Secondary AC | Q96NZ6 |
| UniProt Entry Name | STAT4_HUMAN |
| Gene Symbol | STAT4 |
| GeneID | 6775 |
| NCBI Accession | NP_003142.1 |
| KEGG | hsa:6775 |
| String | 9606.ENSP00000376134 |
| Molecular Weight | Calculated MW: 86 kDa Observed MW: 76 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |