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STEAP3 Metalloreductase (STEAP3) Antibody
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Catalogue No: abx028683
Price:
US$290.00
(Size: 80 µl)
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Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe (3+) to Fe (2+). Can also reduce of Cu (2+) to Cu (1+), suggesting that it participates in copper homeostasis. Uses NAD (+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
Research Articles on STEAP3 Metalloreductase (STEAP3)
| Target | STEAP3 Metalloreductase (STEAP3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 441-470 amino acids from the C-terminal region of human STEAP3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q658P3 (UniProt, ExPASy) |
| UniProt Entry Name | STEA3_HUMAN |
| KEGG | hsa:55240 |
| String | 9606.ENSP00000376822 |
| Molecular Weight | Calculated MW: 54.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |