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Syntaxin-1A (STX1A) Antibody
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Catalogue No: abx034527
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein) Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis.
Research Articles on Syntaxin-1A (STX1A)
| Target | Syntaxin-1A (STX1A) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human STX1A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q16623 (UniProt, ExPASy) |
| UniProt Secondary AC | O15447, O15448, Q12936, Q75MD9, Q7Z5K3, Q9BPZ6 |
| UniProt Entry Name | STX1A_HUMAN |
| KEGG | hsa:6804 |
| String | 9606.ENSP00000222812 |
| Molecular Weight | Calculated MW: 33 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat STX1A. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |