+44 (0) 1223 755950
+1 832 327 7413
SUFU Negative Regulator of Hedgehog Signaling (SUFU) Antibody
REQUEST MORE INFO
Catalogue No: abx005181
Price:
US$203.00
(Size: 20 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
SUFU Antibody is a Rabbit Polyclonal antibody against SUFU. The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
Research Articles on SUFU Negative Regulator of Hedgehog Signaling (SUFU)
| Target | SUFU Negative Regulator of Hedgehog Signaling (SUFU) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 325-484 of human SUFU. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UMX1 (UniProt, ExPASy) |
| UniProt Secondary AC | Q7LCP7, Q9NT90, Q9NZ07, Q9UHK2, Q9UHM8, Q9UMY0 |
| UniProt Entry Name | SUFU_HUMAN |
| Gene Symbol | SUFU |
| GeneID | 51684 |
| NCBI Accession | NP_057253.2 |
| String | 9606.ENSP00000358918 |
| Molecular Weight | Calculated MW: 54 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |