Small Ubiquitin Related Modifier Protein 1 (SUMO1) Antibody

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Catalogue No: abx026669
Price: US$290.00
(Size: 80 µl)

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Datasheet SDS
Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. The SUMO family consists of SUMO1 and closely related homologs SUMO2, SUMO3, and SUMO4. Sumoylation has been shown to regulate a wide range of proteins, including MDM2, PIAS, PML, RanGAP1, RanBP2, p53, p73, HIPK2, TEL, c-Jun, Fas, Daxx, TNFRI, Topo-I, Topo-II, PARK2, WRN, Sp100, IkB-alpha, Androgen receptor (AR), GLUT1/4, CaMK, DNMT3B, TDG, HIF1A, CHD3, EXOSC9, RAD51, and viral targets such as CMV-IE1/2, EBV-BZLF1, and HPV/BPV-E1.

Target Small Ubiquitin Related Modifier Protein 1 (SUMO1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 55-86 amino acids from the C-terminal region of human SUMO1.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P63165 (UniProt, ExPASy)
UniProt Secondary AC A8MUS8, B2R4I5, P55856, Q6FGG0, Q6NZ62, Q93068
UniProt Entry Name SUMO1_HUMAN
NCBI Accession NP_001005781.1 NP_001005782.1 NP_003343.1
KEGG hsa:7341
String 9606.ENSP00000376077
Molecular Weight Calculated MW: 11.6 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse, Rat, Cow and Pig SUMO1.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Small Ubiquitin Related Modifier Protein 1 (SUMO1)


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