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Small Ubiquitin Related Modifier Protein 2 (SUMO2) Antibody
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Catalogue No: abx027042
Price:
US$326.25
(Size: 80 µl)
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SUMO2 is a member of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
Research Articles on Small Ubiquitin Related Modifier Protein 2 (SUMO2)
| Target | Small Ubiquitin Related Modifier Protein 2 (SUMO2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 63-93 amino acids from the C-terminal region of human SUMO2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P61956 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R4I2, P55855, Q32Q42, Q6IPZ6, Q96HK1 |
| NCBI Accession | NP_001005849.1 NP_008868.3 |
| KEGG | hsa:6613 |
| Molecular Weight | Calculated MW: 10.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Pig, Hamster, Monkey, Zebrafish and Xenopus SUMO2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |