Superoxide Dismutase (SOD) Antibody

Superoxide Dismutase (SOD) Antibody is a Rabbit Polyclonal antibody for the detection of SOD1.

Superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult) ) (SOD1, synonyms: ALS, SOD, ALS1, IPOA) binds copper and zinc ions and is one of two isozymes responsible for destroying free uperoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.

Target	Superoxide Dismutase (SOD)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	superoxide dismutase 1, soluble
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P00441 (UniProt, ExPASy)
UniProt Entry Name	SODC_HUMAN
GeneID	6647
OMIM	147450
KEGG	hsa:6647
String	9606.ENSP00000270142
Molecular Weight	Observed MW: 16 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Superoxide Dismutase (SOD)

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