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Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) Antibody
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Catalogue No: abx010443
Price:
US$427.75
(Size: 100 µl)
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Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Research Articles on Baculoviral IAP Repeat-Containing Protein 5 (BIRC5)
| Target | Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of Survivin expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O15392 (UniProt, ExPASy) |
| UniProt Entry Name | BIRC5_HUMAN |
| Gene Symbol | BIRC5 |
| GeneID | 332 |
| OMIM | 603352 |
| HGNC | 593 |
| KEGG | hsa:332 |
| Ensembl | ENSG00000089685 |
| Molecular Weight | 16 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |