Survivin (BIRC5) Antibody

Survivin (BIRC5) Antibody is a Mouse Monoclonal antibody for the detection of SURVIVIN.

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Target	Survivin (BIRC5)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	WB: 1/1000 - 1/6000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	SURVIVIN
Isotype	IgG1
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by Protein A and Protein G affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	O15392 (UniProt, ExPASy)
UniProt Entry Name	BIRC5_HUMAN
Gene Symbol	BIRC5
GeneID	332
OMIM	603352
HGNC	593
KEGG	hsa:332
Ensembl	ENSG00000089685
Molecular Weight	Observed MW: 18 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Survivin (BIRC5)

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