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Survivin (BIRC5) Antibody
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Catalogue No: abx239883
Price:
US$406.00
(Size: 100 µg)
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Survivin (BIRC5) Antibody is a Mouse Monoclonal antibody for the detection of SURVIVIN. This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Research Articles on Survivin (BIRC5)
| Target | Survivin (BIRC5) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000 - 1/6000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | SURVIVIN |
| Isotype | IgG1 |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | O15392 (UniProt, ExPASy) |
| UniProt Entry Name | BIRC5_HUMAN |
| Gene Symbol | BIRC5 |
| GeneID | 332 |
| OMIM | 603352 |
| HGNC | 593 |
| KEGG | hsa:332 |
| Ensembl | ENSG00000089685 |
| Molecular Weight | Observed MW: 18 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |