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Suppressor of Variegation 4-20 Homolog 2 (SUV4-20H2) Antibody
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Catalogue No: abx032837
Price:
US$326.25
(Size: 50 µl)
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SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).
Research Articles on Suppressor of Variegation 4-20 Homolog 2 (SUV4-20H2)
| Target | Suppressor of Variegation 4-20 Homolog 2 (SUV4-20H2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 187-214 amino acids from the Central region of human SUV4-20H2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q86Y97 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8WZ10, Q9BRZ6 |
| UniProt Entry Name | KMT5C_HUMAN |
| NCBI Accession | NP_116090.2 |
| KEGG | hsa:84787 |
| String | 9606.ENSP00000255613 |
| Molecular Weight | Calculated MW: 52.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat KMT5C. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |