Spleen Associated Tyrosine Kinase (SYK) Antibody

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Target	Spleen Associated Tyrosine Kinase (SYK)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 268-305 amino acids from human SYK.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P43405 (UniProt, ExPASy)
UniProt Entry Name	KSYK_HUMAN
KEGG	hsa:6850
String	9606.ENSP00000364907
Molecular Weight	Calculated MW: 72.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Pig SYK.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Spleen Associated Tyrosine Kinase (SYK)

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