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Spleen Associated Tyrosine Kinase Phospho-Tyr323 (SYK pY323) Antibody
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Catalogue No: abx000342
Price:
US$551.00
(Size: 100 µl)
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SYK (pY323) Antibody is a Rabbit Polyclonal antibody against SYK (pY323). This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Spleen Associated Tyrosine Kinase Phospho-Tyr323 (SYK pY323)
| Target | Spleen Associated Tyrosine Kinase Phospho-Tyr323 (SYK pY323) |
| Clonality | Polyclonal |
| Target Modification | Tyr323 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A phospho specific peptide corresponding to residues surrounding Y323 of human Syk |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P43405 (UniProt, ExPASy) |
| UniProt Entry Name | KSYK_HUMAN |
| Gene Symbol | SYK |
| GeneID | 6850 |
| KEGG | hsa:6850 |
| String | 9606.ENSP00000364907 |
| Molecular Weight | Calculated MW: 72 kDa Observed MW: 72 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |