T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody

T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E) Antibody is a Rabbit Polyclonal antibody for the detection of CD3 epsilon.

CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells.

Target	T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	CD3e molecule, epsilon (CD3-TCR complex)
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P07766 (UniProt, ExPASy)
UniProt Secondary AC	A8K997
UniProt Entry Name	CD3E_HUMAN
Gene Symbol	CD3E
GeneID	916
OMIM	186830
HGNC	1674
KEGG	hsa:916
Ensembl	ENSG00000198851
String	9606.ENSP00000354566
Molecular Weight	Observed MW: 23 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on T-Cell Surface Glycoprotein CD3 Epsilon Chain (CD3E)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue