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Transcriptional Adaptor 3 (TADA3L) Antibody
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Catalogue No: abx028290
Price:
US$326.25
(Size: 80 µl)
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Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq].
Research Articles on Transcriptional Adaptor 3 (TADA3L)
| Target | Transcriptional Adaptor 3 (TADA3L) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 386-414 amino acids from the C-terminal region of human TADA3L. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O75528 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6FI83, Q9UFS2 |
| UniProt Entry Name | TADA3_HUMAN |
| Gene Symbol | TADA3 |
| KEGG | hsa:10474 |
| String | 9606.ENSP00000307684 |
| Molecular Weight | Calculated MW: 48.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Zebrafish and Xenopus TADA3. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |