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TATA-Box Binding Protein Associated Factor 10 (TAF10) Antibody
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Catalogue No: abx030588
Price:
US$326.25
(Size: 80 µl)
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This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs.
Research Articles on TATA-Box Binding Protein Associated Factor 10 (TAF10)
| Target | TATA-Box Binding Protein Associated Factor 10 (TAF10) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 121-150 amino acids from the Central region of human TAF10. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q12962 (UniProt, ExPASy) |
| UniProt Secondary AC | O00703, Q13175, Q6FH13 |
| UniProt Entry Name | TAF10_HUMAN |
| NCBI Accession | NP_006275.1 |
| KEGG | hsa:6881 |
| String | 9606.ENSP00000299424 |
| Molecular Weight | Calculated MW: 21.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse TAF10. |
| Availability | Please enquire. |
| Note | This product is for research use only. |