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TRAF Family Member-Associated NF-Kappa-B Activator (TANK) Antibody
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Catalogue No: abx005187
Price:
US$348.00
(Size: 60 µl)
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TANK Antibody is a Rabbit Polyclonal antibody against TANK. The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on TRAF Family Member-Associated NF-Kappa-B Activator (TANK)
| Target | TRAF Family Member-Associated NF-Kappa-B Activator (TANK) |
| Clonality | Polyclonal |
| Reactivity | Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human TANK |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q92844 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DPB5, Q7Z4J6, Q92885 |
| UniProt Entry Name | TANK_HUMAN |
| Gene Symbol | TANK |
| GeneID | 10010 |
| NCBI Accession | NP_597841.1 |
| KEGG | hsa:10010 |
| String | 9606.ENSP00000376505 |
| Molecular Weight | Calculated MW: 13 kDa/47 kDa Observed MW: 48 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |