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Antigen Peptide Transporter 1 (TAP1) Antibody
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Catalogue No: abx004748
Price:
US$797.50
(Size: 96 tests)
Orders to United States ship from United States
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TAP1 Antibody is a Rabbit Polyclonal antibody against TAP1. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Antigen Peptide Transporter 1 (TAP1)
| Target | Antigen Peptide Transporter 1 (TAP1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 524-808 of human TAP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q03518 (UniProt, ExPASy) |
| UniProt Secondary AC | Q16149, Q96CP4 |
| UniProt Entry Name | TAP1_HUMAN |
| Gene Symbol | TAP1 |
| GeneID | 6890 |
| NCBI Accession | NP_000584.3 |
| KEGG | hsa:6890 |
| String | 9606.ENSP00000346206 |
| Molecular Weight | Calculated MW: 81 kDa Observed MW: 68 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
