Antigen Peptide Transporter 2 (TAP2) Antibody

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Catalogue No: abx117122
Price: US$522.00
(Size: 100 µl)

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Antigen Peptide Transporter 2 (TAP2) Antibody

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Datasheet SDS
TAP2 Antibody is a Rabbit Polyclonal antibody against TAP2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transportersABC proteins transport various molecules across extra- and intra-cellular membranesABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White)This protein is a member of the MDR/TAP subfamilyMembers of the MDR/TAP subfamily are involved in multidrug resistanceThis gene is located 7 kb telomeric to gene family member ABCB2The protein encoded by this gene is involved in antigen presentationThis protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulumMutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac diseaseAlternative splicing of this gene produces two products which differ in peptide selectivity and level of restoRation of surface expression of MHC class I molecules.

Target Antigen Peptide Transporter 2 (TAP2)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TAP2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q03519 (UniProt, ExPASy)
UniProt Secondary AC B0V2J8, O95410, Q53FI6, Q5HY71, Q96PT8, Q9UQ83
UniProt Entry Name TAP2_HUMAN
Gene Symbol TAP2
GeneID 6891
KEGG hsa:6891
String 9606.ENSP00000364034
Buffer PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Antigen Peptide Transporter 2 (TAP2)


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