TAR DNA-Binding Protein 43 / TDP43 (TARDBP) Antibody

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq].

Target	TAR DNA-Binding Protein 43 / TDP43 (TARDBP)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/2000, IHC-P: 1/100, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TARDBP.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13148 (UniProt, ExPASy)
UniProt Entry Name	TADBP_HUMAN
NCBI Accession	NP_031401.1
KEGG	hsa:23435
String	9606.ENSP00000240185
Molecular Weight	Calculated MW: 44.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Chicken TARDBP.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on TAR DNA-Binding Protein 43 / TDP43 (TARDBP)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue