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T-Box Protein 1 (TBX1) Antibody
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Catalogue No: abx034348
Price:
US$326.25
(Size: 80 µl)
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TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS) /velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Research Articles on T-Box Protein 1 (TBX1)
| Target | T-Box Protein 1 (TBX1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/25, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 327-356 amino acids from the C-terminal region of human TBX1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O43435 (UniProt, ExPASy) |
| UniProt Secondary AC | C6G493, C6G494, O43436, Q96RJ2 |
| UniProt Entry Name | TBX1_HUMAN |
| Gene Symbol | TBX1 |
| NCBI Accession | NP_005983.1 NP_542377.1 NP_542378.1 |
| KEGG | hsa:6899 |
| String | 9606.ENSP00000331791 |
| Molecular Weight | Calculated MW: 43.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |