T-Box Transcription Factor TBX21 (TBX21) Antibody

TBX21 Antibody is a Rabbit Polyclonal antibody against TBX21. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.

Target	T-Box Transcription Factor TBX21 (TBX21)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 322-535 of human TBX21.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UL17 (UniProt, ExPASy)
UniProt Entry Name	TBX21_HUMAN
Gene Symbol	TBX21
GeneID	30009
NCBI Accession	NP_037483.1
String	9606.ENSP00000177694
Molecular Weight	Calculated MW: 58 kDa Observed MW: 58 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on T-Box Transcription Factor TBX21 (TBX21)

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