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T-Box Protein 5 (TBX5) Antibody
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Catalogue No: abx011599
Price:
US$427.75
(Size: 100 µl)
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TBX5, also known as T-box 5. It is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The TBX5 protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.
Research Articles on T-Box Protein 5 (TBX5)
| Target | T-Box Protein 5 (TBX5) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of TBX5 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q99593 (UniProt, ExPASy) |
| UniProt Secondary AC | A6ND77, O15301, Q96TB0, Q9Y4I2 |
| UniProt Entry Name | TBX5_HUMAN |
| Gene Symbol | TBX5 |
| GeneID | 6910 |
| OMIM | 142900 |
| HGNC | 11604 |
| KEGG | hsa:6910 |
| Ensembl | ENSG00000089225 |
| String | 9606.ENSP00000309913 |
| Molecular Weight | 53 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |