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Thromboxane-A Synthase (TBXAS1) Antibody
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Catalogue No: abx001620
Price:
US$203.00
(Size: 20 µl)
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TBXAS1 Antibody is a Rabbit Polyclonal antibody against TBXAS1. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Thromboxane-A Synthase (TBXAS1)
| Target | Thromboxane-A Synthase (TBXAS1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 355-534 of human Thromboxane synthase. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P24557 (UniProt, ExPASy) |
| UniProt Entry Name | THAS_HUMAN |
| Gene Symbol | TBXAS1 |
| GeneID | 6916 |
| NCBI Accession | NP_001052.2 |
| KEGG | hsa:6916 |
| String | 9606.ENSP00000389414 |
| Molecular Weight | Calculated MW: 61 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |