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Transcription Elongation Factor B Subunit 2 (TCEB2) Antibody
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Catalogue No: abx027966
Price:
US$326.25
(Size: 80 µl)
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This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13.
Research Articles on Transcription Elongation Factor B Subunit 2 (TCEB2)
| Target | Transcription Elongation Factor B Subunit 2 (TCEB2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 21-48 amino acids from the Central region of human TCEB2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15370 (UniProt, ExPASy) |
| UniProt Secondary AC | B7WPD3 |
| UniProt Entry Name | ELOB_HUMAN |
| KEGG | hsa:6923 |
| String | 9606.ENSP00000262306 |
| Molecular Weight | Calculated MW: 13.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |