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Transcription Elongation Factor B Subunit 2 (TCEB2) Antibody
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Catalogue No: abx004103
Price:
US$217.50
(Size: 20 µl)
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TCEB2 Antibody is a Rabbit Polyclonal antibody against TCEB2. This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13.
Research Articles on Transcription Elongation Factor B Subunit 2 (TCEB2)
| Target | Transcription Elongation Factor B Subunit 2 (TCEB2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human TCEB2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15370 (UniProt, ExPASy) |
| UniProt Secondary AC | B7WPD3 |
| UniProt Entry Name | ELOB_HUMAN |
| Gene Symbol | ELOB |
| GeneID | 6923 |
| NCBI Accession | NP_009039.1 |
| KEGG | hsa:6923 |
| String | 9606.ENSP00000262306 |
| Molecular Weight | Calculated MW: 13 kDa Observed MW: 18 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |