Transcription Factor E2-Alpha (TCF3) Antibody

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Catalogue No: abx010676
Price: US$427.75
(Size: 100 µl)

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Datasheet SDS
E2A is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa -E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.

Target Transcription Factor E2-Alpha (TCF3)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human TCF3 expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P15923 (UniProt, ExPASy)
UniProt Secondary AC P15883, Q14208, Q14635, Q14636, Q2TB39, Q2TB40, Q9UPI9
UniProt Entry Name TFE2_HUMAN
Gene Symbol TCF3
GeneID 6929
OMIM 147141
HGNC 11633
KEGG hsa:6929
Ensembl ENSG00000071564
String 9606.ENSP00000262965
Molecular Weight 67.6 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Transcription Factor E2-Alpha (TCF3)
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