T-Cell Leukemia/lymphoma Protein 1A (TCL1A) Antibody

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Catalogue No: abx000786
Price: US$217.50
(Size: 20 µl)
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Western blot analysis of lysates from Ramos cells, using TCL1A Antibody at 1/1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
T-Cell Leukemia/lymphoma Protein 1A (TCL1A) Antibody

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Datasheet SDS
TCL1A Antibody is a Rabbit Polyclonal antibody against TCL1A. Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements. In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730).

Target T-Cell Leukemia/lymphoma Protein 1A (TCL1A)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human TCL1A.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P56279 (UniProt, ExPASy)
UniProt Secondary AC Q6IBK7
UniProt Entry Name TCL1A_HUMAN
Gene Symbol TCL1A
GeneID 8115
NCBI Accession NP_001092195.1
KEGG hsa:8115
String 9606.ENSP00000385036
Molecular Weight Calculated MW: 13 kDa
Observed MW: 16 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on T-Cell Leukemia/lymphoma Protein 1A (TCL1A)
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