Transcription Factor AP-2 Alpha (TFAP2A) Antibody

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Catalogue No: abx031199
Price: US$326.25
(Size: 80 µl)

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Transcription Factor AP-2 Alpha (TFAP2A) Antibody

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Datasheet SDS
TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.

Target Transcription Factor AP-2 Alpha (TFAP2A)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 407-436 amino acids from the C-terminal region of human TFAP2A.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P05549 (UniProt, ExPASy)
UniProt Secondary AC Q13777, Q5TAV5, Q8N1C6
UniProt Entry Name AP2A_HUMAN
KEGG hsa:7020
String 9606.ENSP00000368924
Molecular Weight Calculated MW: 48.1 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Cow TFAP2A.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Transcription Factor AP-2 Alpha (TFAP2A)
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