Tissue Factor Pathway Inhibitor (TFPI) Antibody

TFPI Antibody is a Rabbit Polyclonal antibody against TFPI. This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq, Jul 2008].

Target	Tissue Factor Pathway Inhibitor (TFPI)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 29-224 of human TFPI.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P10646 (UniProt, ExPASy)
UniProt Secondary AC	O95103, Q53TS4
UniProt Entry Name	TFPI1_HUMAN
Gene Symbol	TFPI
GeneID	7035
NCBI Accession	NP_001027452.1
KEGG	hsa:7035
String	9606.ENSP00000233156
Molecular Weight	Calculated MW: 35 kDa Observed MW: 34 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tissue Factor Pathway Inhibitor (TFPI)

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