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Transforming Growth Factor Beta Receptor 2 (TGFBR2) Antibody
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Catalogue No: abx026476
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Research Articles on Transforming Growth Factor Beta Receptor 2 (TGFBR2)
| Target | Transforming Growth Factor Beta Receptor 2 (TGFBR2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/25, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human TGFBR2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P37173 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DTV5, Q15580, Q6DKT6, Q99474 |
| UniProt Entry Name | TGFR2_HUMAN |
| Gene Symbol | TGFBR2 |
| KEGG | hsa:7048 |
| String | 9606.ENSP00000351905 |
| Molecular Weight | Calculated MW: 64.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |