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Transforming Growth Factor Beta Receptor 2 (TGFBR2) Antibody
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Catalogue No: abx001227
Price:
US$217.50
(Size: 20 µl)
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TGFBR2 Antibody is a Rabbit Polyclonal antibody against TGFBR2. This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Research Articles on Transforming Growth Factor Beta Receptor 2 (TGFBR2)
| Target | Transforming Growth Factor Beta Receptor 2 (TGFBR2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 23-280 of human TGF beta Receptor II (TGFBR2). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P37173 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DTV5, Q15580, Q6DKT6, Q99474 |
| UniProt Entry Name | TGFR2_HUMAN |
| Gene Symbol | TGFBR2 |
| GeneID | 7048 |
| NCBI Accession | NP_003233.4 |
| KEGG | hsa:7048 |
| String | 9606.ENSP00000351905 |
| Molecular Weight | Calculated MW: 65 kDa Observed MW: 70/65/85 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |