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Protein-Glutamine Gamma-Glutamyltransferase 2 (TGM2) Antibody
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Catalogue No: abx000934
Price:
US$217.50
(Size: 20 µl)
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TGM2 Antibody is a Rabbit Polyclonal antibody against TGM2. Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Protein-Glutamine Gamma-Glutamyltransferase 2 (TGM2)
| Target | Protein-Glutamine Gamma-Glutamyltransferase 2 (TGM2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 299-548 of human Transglutaminase 2 (TGM2). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P21980 (UniProt, ExPASy) |
| UniProt Secondary AC | E1P5V9, Q16436, Q6B838, Q9BTN7, Q9H035, Q9UH35 |
| UniProt Entry Name | TGM2_HUMAN |
| Gene Symbol | TGM2 |
| GeneID | 7052 |
| NCBI Accession | NP_945189.1 |
| KEGG | hsa:7052 |
| String | 9606.ENSP00000355330 |
| Molecular Weight | Calculated MW: 77 kDa Observed MW: 77 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1.16 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |