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Thyroid Hormone Receptor Beta (THRB) Antibody
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Catalogue No: abx001332
Price:
US$348.00
(Size: 60 µl)
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THRB Antibody is a Rabbit Polyclonal antibody against THRB. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008].
Research Articles on Thyroid Hormone Receptor Beta (THRB)
| Target | Thyroid Hormone Receptor Beta (THRB) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human THRB |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P10828 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KU79, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41 |
| UniProt Entry Name | THB_HUMAN |
| Gene Symbol | THRB |
| GeneID | 7068 |
| NCBI Accession | NP_000452.2 |
| KEGG | hsa:7068 |
| String | 9606.ENSP00000379904 |
| Molecular Weight | Calculated MW: 52 kDa/54 kDa Observed MW: 53 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |