Toll Like Receptor Adaptor Molecule 1 (TICAM1) Antibody

TICAM1 Antibody is a Rabbit Polyclonal antibody against TICAM1. This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.

Target	Toll Like Receptor Adaptor Molecule 1 (TICAM1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 180-280 of human TRIF / TICAM1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8IUC6-1 (UniProt, ExPASy)
UniProt Secondary AC	B3Y691, O75532, Q86XP8, Q96GA0
UniProt Entry Name	TCAM1_HUMAN
Gene Symbol	TICAM1
GeneID	148022
NCBI Accession	NP_891549.1
Molecular Weight	Calculated MW: 76 kDa Observed MW: 75 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Toll Like Receptor Adaptor Molecule 1 (TICAM1)

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