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Probable Fructose-2,6-Bisphosphatase TIGAR (TIGAR) Antibody
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Catalogue No: abx030844
Price:
US$326.25
(Size: 80 µl)
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This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2, 6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq].
Research Articles on Probable Fructose-2,6-Bisphosphatase TIGAR (TIGAR)
| Target | Probable Fructose-2,6-Bisphosphatase TIGAR (TIGAR) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TIGAR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9NQ88 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R840 |
| UniProt Entry Name | TIGAR_HUMAN |
| Gene Symbol | TIGAR |
| String | 9606.ENSP00000179259 |
| Molecular Weight | Calculated MW: 30.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |