Metalloproteinase Inhibitor 1 (TIMP1) Antibody

TIMP1 Antibody detects endogenous levels of total TIMP1. TIMP1 Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16.

Target	Metalloproteinase Inhibitor 1 (TIMP1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Synthesised peptide derived from human TIMP1
Form	Liquid
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01033 (UniProt, ExPASy)
UniProt Secondary AC	Q14252, Q9UCU1
UniProt Entry Name	TIMP1_HUMAN
Gene Symbol	TIMP1
KEGG	hsa:7076
Ensembl	ENSG00000102265
String	9606.ENSP00000218388
Molecular Weight	24 kDa
Buffer	PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Specificity	TIMP1 Antibody detects endogenous levels of total TIMP1
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Metalloproteinase Inhibitor 1 (TIMP1)

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