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Transducin-Like Enhancer Protein 1 (TLE1) Antibody
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Catalogue No: abx025357
Price:
US$326.25
(Size: 80 µl)
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Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Research Articles on Transducin-Like Enhancer Protein 1 (TLE1)
| Target | Transducin-Like Enhancer Protein 1 (TLE1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 199-228 amino acids from the Central region of human TLE1. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q04724 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K495, Q5T3G4, Q969V9 |
| UniProt Entry Name | TLE1_HUMAN |
| KEGG | hsa:7088 |
| String | 9606.ENSP00000365682 |
| Molecular Weight | Calculated MW: 83.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |