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Toll-Like Receptor 1 (TLR1) Antibody
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Catalogue No: abx000950
Price:
US$348.00
(Size: 60 µl)
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TLR1 Antibody is a Rabbit Polyclonal antibody against TLR1. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.
Research Articles on Toll-Like Receptor 1 (TLR1)
| Target | Toll-Like Receptor 1 (TLR1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human TLR1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15399 (UniProt, ExPASy) |
| UniProt Secondary AC | D1CS39, D1CS41, O15452, Q32MK3, Q32MK4, Q9UG90 |
| UniProt Entry Name | TLR1_HUMAN |
| Gene Symbol | TLR1 |
| GeneID | 7096 |
| OMIM | 601194 |
| NCBI Accession | NP_003254.2 |
| HGNC | 11847 |
| KEGG | hsa:7096 |
| Ensembl | ENSG00000174125 |
| String | 9606.ENSP00000354932 |
| Molecular Weight | Calculated MW: 90 kDa Observed MW: 100 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |