Toll-Like Receptor 1 (TLR1) Antibody

TLR1 Antibody is a Rabbit Polyclonal antibody against TLR1. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.

Target	Toll-Like Receptor 1 (TLR1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 30-290 of human TLR1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15399 (UniProt, ExPASy)
UniProt Secondary AC	D1CS39, D1CS41, O15452, Q32MK3, Q32MK4, Q9UG90
UniProt Entry Name	TLR1_HUMAN
Gene Symbol	TLR1
GeneID	7096
OMIM	601194
NCBI Accession	NP_003254.2
HGNC	11847
KEGG	hsa:7096
Ensembl	ENSG00000174125
String	9606.ENSP00000354932
Molecular Weight	Calculated MW: 90 kDa Observed MW: 90 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Toll-Like Receptor 1 (TLR1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue