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Transmembrane Protein 173 (TM173) Antibody
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Catalogue No: abx034495
Price:
US$326.25
(Size: 80 µl)
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Acts as a facilitator of innate immune signaling. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
Research Articles on Transmembrane Protein 173 (TM173)
| Target | Transmembrane Protein 173 (TM173) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 311-340 amino acids from the C-terminal region of human TM173. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q86WV6 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K3P6, B6EB35, D6RBX0, D6RE01, D6RID9 |
| UniProt Entry Name | STING_HUMAN |
| Gene Symbol | TMEM173 |
| KEGG | hsa:340061 |
| String | 9606.ENSP00000331288 |
| Molecular Weight | Calculated MW: 42.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |