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Transmembrane Channel Like 8 (TMC8) Antibody
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Catalogue No: abx027907
Price:
US$290.00
(Size: 80 µl)
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Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs.
Research Articles on Transmembrane Channel Like 8 (TMC8)
| Target | Transmembrane Channel Like 8 (TMC8) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human TMC8. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q8IU68 (UniProt, ExPASy) |
| UniProt Secondary AC | Q2YDC0, Q8IWU7, Q8N358, Q8NF04 |
| UniProt Entry Name | TMC8_HUMAN |
| Gene Symbol | TMC8 |
| KEGG | hsa:147138 |
| String | 9606.ENSP00000325561 |
| Molecular Weight | Calculated MW: 81.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |