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Transmembrane Emp24 Domain-Containing Protein 10 (TMED10) Antibody
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Catalogue No: abx030884
Price:
US$326.25
(Size: 80 µl)
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This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Research Articles on Transmembrane Emp24 Domain-Containing Protein 10 (TMED10)
| Target | Transmembrane Emp24 Domain-Containing Protein 10 (TMED10) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 156-185 amino acids from the C-terminal region of human TMED10. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P49755 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R605, Q15602, Q16536, Q86TC2, Q86TS5 |
| UniProt Entry Name | TMEDA_HUMAN |
| KEGG | hsa:10972 |
| String | 9606.ENSP00000303145 |
| Molecular Weight | Calculated MW: 25 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Rabbit TMED10. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |