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Transmembrane Emp24 Domain-Containing Protein 10 (TMED10) Antibody
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Catalogue No: abx005193
Price:
US$797.50
(Size: 96 tests)
Orders to United States ship from United States
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TMED10 Antibody is a Rabbit Polyclonal antibody against TMED10. This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Research Articles on Transmembrane Emp24 Domain-Containing Protein 10 (TMED10)
| Target | Transmembrane Emp24 Domain-Containing Protein 10 (TMED10) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 35-190 of human TMED10. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P49755 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R605, Q15602, Q16536, Q86TC2, Q86TS5 |
| UniProt Entry Name | TMEDA_HUMAN |
| Gene Symbol | TMED10 |
| GeneID | 10972 |
| NCBI Accession | NP_006818.3 |
| KEGG | hsa:10972 |
| String | 9606.ENSP00000303145 |
| Molecular Weight | Calculated MW: 25 kDa Observed MW: 21 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
